Intermittent Living: the use of ancient challenges as a vaccine against the deleterious effect od modern life - A hypothesis

Chronic non-communicable diseases (CNCD) are the leading cause of mortality in developed countries. They ensue from the sum of modern anthropogenic risk factors, including high calorie nutrition, malnutrition, se- dentary lifestyle, social stress, environmental toxins, politics and economic factors. Many of these factors are beyond the span of control of individuals, suggesting that CNCD are inevitable. However, various studies, ours included, show that the use of intermittent challenges with hormetic effects improve subjective and objective well-being of individuals with CNCD, while having favourable effects on immunological, metabolic and beha- vioural indices. Intermittent cold, heat, fasting and....
Leo Pruimboom, Frits A.J. Muskiet, Vaccine 2018 (PDF)

The benefits of INTERMITTENT FASTING

Meal frequency and timing in health and disease. M.P. Mattson

Restoring insulin sensitivity to maintain cognitive skills is so important

Hormesis:

npj Aging and Mechanisms of Disease (2017)3:13 ; doi:10.1038/s41514-017-0013-z

The influence of sleep on inflammation levels and thus on the development of diseases

https://drive.google.com/file/d/1HDhXb_PZXjQL8DQiPAJRStLa-Jc6rppT/view

https://pubmed.ncbi.nlm.nih.gov/25714703/

https://academic.oup.com/jcem/article/89/5/2119/2844257

Evidence-Based Health & Wellness

At Flex Health Academy, we believe that real transformation is built on both experience and science.

Below, you’ll find a curated collection of scientific research supporting the methods we work with. From light therapy and breathwork to acupuncture and movement — each approach is grounded in evidence and ongoing research.

 
Source: Hamblin, M. R. (2017). Mechanisms and applications of the anti-inflammatory effects of photobiomodulation. AIMS Biophysics, 4(3), 337–361. 
  
Source: Salehpour, F., et al. (2018). Brain Photobiomodulation Therapy: a Narrative Review. Molecular Neurobiology, 55(8), 6601–6636. 
  
Source: Avci, P., et al. (2013). Low-Level Laser (Light) Therapy (LLLT) in Skin: Stimulating, Healing, Restoring. Seminars in Cutaneous Medicine and Surgery, 32(1), 41–52. 
  
Source: Ferraresi, C., et al. (2016). Photobiomodulation in human muscle tissue: an advantage in sports performance? Journal of Biophotonics, 9(11-12), 1273–1299. 
  
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Source: Vickers, A. J., et al. (2018). Acupuncture for Chronic Pain: Update of an Individual Patient Data Meta-Analysis. The Journal of Pain, 19(5), 455–474. 
  
Source: Arranz, L., et al. (2021). Neuroinmunomodulation of Acupuncture in Major Depressive Disorder: A Review. Frontiers in Psychiatry, 12, 668416. 
  
Source: Kim, T.-H., et al. (2021). The Role of Acupuncture in the Treatment of Inflammatory Diseases. Evidence-Based Complementary and Alternative Medicine, 2021, 1-2. 
  
Source: Zhu, J., et al. (2021). Acupuncture for Irritable Bowel Syndrome: Systematic Review and Meta-Analysis. Medicine, 100(14), e25419. 
  
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Source: Zaccaro, A., et al. (2018). How Breath-Control Can Change Your Life: A Systematic Review on Psycho-Physiological Correlates of Slow Breathing. Frontiers in Human Neuroscience, 12, 353. 
  
Source: Balban, M. Y., et al. (2023). Brief structured respiration practices enhance mood and reduce physiological arousal. Cell Reports Medicine, 4(1), 100895. 
  
Source: Yackle, K., et al. (2017). Breathing Control Center Neurons that Promote Arousal in Mice. Science, 355(6332), 1411–1415. 
  
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Source: Ross, A., & Thomas, S. (2010). The health benefits of yoga and exercise: a review of comparison studies. Journal of Alternative and Complementary Medicine, 16(1), 3–12. 
  
Source: Woodyard, C. (2011). Exploring the therapeutic effects of yoga and its ability to increase quality of life. International Journal of Yoga, 4(2), 49–54. 
  
Source: Streeter, C. C., et al. (2020). Effects of Yoga on the Autonomic Nervous System, Gamma-Aminobutyric Acid, and Allostasis in Epilepsy, Depression, and Post-Traumatic Stress Disorder. Medical Hypotheses, 138, 109585. 
  
Source: Cramer, H., et al. (2018). The Effects of Yoga on Positive Mental Health: A Systematic Review and Meta-Analysis. Journal of Alternative and Complementary Medicine, 24(5), 1–7. 
  
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Source: Martorell, A. J., et al. (2019). Multi-sensory Gamma Stimulation Ameliorates Alzheimer’s-Associated Pathology and Improves Cognition. Cell, 177(2), 256–271. 
  
Source: Becquet, D., et al. (2021). Auditory stimulation of sleep slow oscillations enhances memory consolidation in older adults. Frontiers in Neuroscience, 15, 578. 
  
Source: Clements-Cortes, A., & Bartel, L. (2018). Are we doing more than just making sounds? A review of the neurophysiological mechanisms of music therapy. Music and Medicine, 10(3), 124–129. 
  
Source: Lee, H., et al. (2022). Gamma frequency sensory stimulation in probable Alzheimer’s dementia patients: a preliminary report. Journal of Alzheimer's Disease, 87(3), 1–9. 
  
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Source: Nielsen, A., et al. (2007). The effect of Gua Sha treatment on the microcirculation of surface tissue: a pilot study in healthy subjects. Journal of Complementary and Integrative Medicine, 4(1). 
  
Source: Braun, M., et al. (2011). Effectiveness of traditional Chinese "Gua Sha" therapy in patients with chronic neck pain: a randomized controlled trial. Pain Medicine, 12(3), 362–369. 
  
Source: Nielsen, A. (2013). Gua Sha research and the language of integration. Journal of Bodywork and Movement Therapies, 17(1), 1–6. 
  
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Source: Schleip, R. et al. (2019). Fascia as a sensory organ: Implications for manual therapy. Journal of Bodywork and Movement Therapies, 23(3), 43–47. 
  
Source: Okamoto, T. et al. (2020). Connective tissue massage modulates autonomic nervous system and improves mental health in healthy subjects. Journal of Physical Therapy Science, 32(2), 62–66. 
  
Source: Castro-Sánchez, A. M. et al. (2016). Benefits of connective tissue massage in patients with fibromyalgia: a systematic review. Evidence-Based Complementary and Alternative Medicine, 2016. 
  
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Source: National Health Service (NHS). (2021). Physiotherapy: How it works. 
  
Source: Geneen, L. J. et al. (2017). Physical activity and exercise for chronic pain in adults: an overview of Cochrane Reviews. Cochrane Database of Systematic Reviews, 4(CD011279). 
  
Source: American Physical Therapy Association (APTA). (2020). Guide to Physical Therapist Practice.